Thanks for all your help!
Sorry, I should've probably elaborated a bit more. It is going to be used for a car repair garage holding up to 6 vehicles at any one point. There are 6 large bay doors (14' x 16'). Also there are two 40'x5' work pits that are 4' under grade. I have attached a drawing showing the building layout (ignore the part on the right)
I also made a typo, the wall insulation is actually R-12. Roof insulation is R-25, perimeter is R-20. The building height is 22'. There are no windows. The slab itself will be a 6" slab, with gravel / sand compacted underneath. There will be rebar reinforcement.
Yesterday, the engineering company just came back and recommended an additional heating unit and ventillation system for the repair bay calling for 1 complete air change per hour (160000cfh) for the entire garage. They specified that we get another boiler that puts out an additional 250,000BTU/hr and a few RTU's that can handle 160,000cfh.
Does this sound reasonable or should i be looking elsewhere?