sorry hit a wrong button!!
Some people prescribe to the idea of using the bathroom fans to meet the ventilation rate but do not allow for make up air to enter the home. If your house is very tight then the natural air leakage for this to work will not be available. A blower door test can help to determine if the house leaks enough to allow this to work. To aire on the side of caution I would install two seperate systems one to handle the basement and one to handle the first and second floor. dedicated duck work sized to meet the air flow required and balanced return ducks are needed. Not complicated if you know how to properly size and install duct work. allowing for loss of flow factors for corners and length then then you will be able for figure it out. typically 6" returns located in kithen/bath and laundry areas as well as basement. and supplies running to the other areas of the house. They should be sized to handle the air flow requirements for the individual space under the same minimum exchange rate as used to determine total system requirements.
Don't forget that whenever you open your windows the HRV/ERV system does not need to be running, turn it off. In some areas of the country this might be 50% of the time. No need to waste energy on a ventilation system running when nature takes it's course.
Tom Pittsley
[email protected] www.eebt.org